A Study of Econoglutide Injection in Obese Participants With Knee Osteoarthritis (KOA)
NCT07734311 · Not yet recruiting
Last updated 2026-08-27This clinical trial is testing the effects of the drug Econoglutide Injection in adults who are obese and have knee osteoarthritis.
Status Not yet recruiting Approved but enrollment has not started.
Phase Phase 3 Confirms effectiveness in a large group before approval.
Type Interventional (clinical trial)
Design Randomized, double-blind treatment study
Participants 360 people Planned (estimated).
Who can join Ages 18–75 · all sexes
Timeline Started 2026-07 · est. completion 2028-06
Where 1 site · China
What this study is testing ClinicalTrials.gov NCT07734311 ↗
Description as written by the study sponsor.
The main purpose of the study is to evaluate the efficacy and safety of ecnoglutide injections versus placebo in obese participants with KOA.
Treatments tested
- Ecnoglutide Injection Drug
subcutaneous injection
- placebo with matching volume Drug
subcutaneous injection
| Main thing measured | Change in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Subscale Score |
|---|---|
| Sponsor | Hangzhou Sciwind Biosciences Co., Ltd. |
| Conditions studied | Knee Osteoarthritis, Obesity |
| GLP-1 drugs | — |
Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT07734311 ↗