Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity

NCT07504172 · Not yet recruiting

Last updated 2026-05-28

This clinical trial is studying how well the medication tirzepatide works in reducing weight in adults who are overweight or have obesity.

Status Not yet recruiting Approved but enrollment has not started.

Type Observational

Participants 1,700 people Planned (estimated).

Who can join Ages 18+ · all sexes

Timeline Started 2026-04 · est. completion 2026-08

Where 10 sites · Netherlands

What this study is testing ClinicalTrials.gov NCT07504172 ↗

Description as written by the study sponsor.

Tirzepatide is one of the new medications for the treatment of obesity. In clinical research people treated with Tirzepatide have weight loss up to 21%. But there is only a little bit of research showing the effect of Tirzepatide in clinical practice. In this retrospective observational study the investigators will evaluate the effectiveness of tirzepatide in routine clinical practice among adults with obesity in the Netherlands.The main questions it aims to answer are: * How much weight do patients lose after six months of treatment with tirzepatide combined with lifestyle coaching? * How is the medication dosed in daily practice? Researchers will use data from electronic health records of patients in multiple outpatient locations of the Dutch Obesity Clinic (NOK, Nederlandse Obesitas Kliniek).

Treatments tested

Tirzepatide also known as Mounjaro Drug

Initiating treatment with tirzepatide

Main thing measured	Weight change
Sponsor	Radboud University Medical Center
Conditions studied	Overweight , Obesity, Obesity (Disorder)
GLP-1 drugs	tirzepatide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT07504172 ↗