Assessing Biological Aging in a Real-World Medical Weight Loss Program Using the LinAge2 Clinical Clock

NCT07444073 · Not yet recruiting

Last updated 2026-05-28

This clinical trial is testing a tool called the LinAge2 Clinical Clock to measure biological aging in adults who are participating in a real-world medical weight loss program.

Status Not yet recruiting Approved but enrollment has not started.

Type Observational

Participants 440 people Planned (estimated).

Who can join Ages 40–89 · all sexes

Timeline Started 2026-02 · est. completion 2026-12

Where 2 sites · Singapore

What this study is testing ClinicalTrials.gov NCT07444073 ↗

Description as written by the study sponsor.

This study examines whether routine treatment with semaglutide or tirzepatide, prescribed with lifestyle coaching in a real-world weight-management program, is associated with changes in biological age measured by the LinAge2 clinical aging clock over 6 months.

Treatments tested

Not applicable. This is an observational study. Other

Not applicable. This is an observational study.

Main thing measured	LinAge2 Biological Age
Sponsor	National University of Singapore
Conditions studied	Aging, Obesity & Overweight
GLP-1 drugs	—

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT07444073 ↗