A Study in Healthy People or Otherwise Healthy With Overweight or Obesity to Compare 2 Formulations of Survodutide Given in Different Ways, Either as a Pre-filled Syringe or a Pen-like Injector

NCT07413913 · Active, not recruiting

Last updated 2026-05-28

This clinical trial compares how two different injection methods (a pre-filled syringe or a pen-like injector) of survodutide affect the drug's levels in the bloodstream of healthy people or those with overweight or obesity.

Status Active, not recruiting Ongoing, but no longer enrolling new participants.

Phase Phase 1 Checks safety and dosing in a small group.

Type Interventional (clinical trial)

Design Randomized, open-label (no blinding) treatment study

Participants 56 people

Who can join Ages 18–55 · all sexes Healthy volunteers accepted.

Timeline Started 2026-03 · est. completion 2026-06

Where 1 site · Germany

What this study is testing ClinicalTrials.gov NCT07413913 ↗

Description as written by the study sponsor.

The goal of this study is to find out whether different formulations of survodutide given by different delivery methods is taken up in the body in a similar way. Participants visit the study site regularly. During study visits, the doctors collect information about participants' health. To assess the study endpoints, participants regularly have blood samples taken.

Treatments tested

Survodutide formulation A also known as BI 456906 Combination Product

Pre-filled syringe
Survodutide formulation B2 also known as BI 456906 Combination Product

Pre-filled pen

Main thing measured	Area under the concentration-time curve of the analyte in plasma over the time interval from 0 to the last quantifiable data point (AUC0-tz)
Sponsor	Boehringer Ingelheim
Conditions studied	Healthy, Obesity
GLP-1 drugs	survodutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT07413913 ↗