Side-to-Side Duodeno-ileostomy Versus Semaglutide in Adults With Obesity and Type 2 Diabetes

NCT07317115 · Recruiting

Last updated 2026-05-28

This clinical trial compares a surgical procedure called side-to-side duodeno-ileostomy with the medication semaglutide in adults who have both obesity and type 2 diabetes to see which may better improve blood sugar control.

Status Recruiting Currently enrolling participants.

Phase Not applicable Not a phased drug trial (e.g. a device or behavioral study).

Type Interventional (clinical trial)

Design Randomized, open-label (no blinding) treatment study

Participants 20 people Planned (estimated).

Who can join Ages 18+ · all sexes

Timeline Started 2026-03 · est. completion 2028-06

Where 1 site · Canada

What this study is testing ClinicalTrials.gov NCT07317115 ↗

Description as written by the study sponsor.

Compare use of the Magnet System in side-to-side duodeno-ileostomy (Surgery) with semaglutide (Medication).

Treatments tested

Magnet System Device

Magnet System for side-to-side magnetic compression anastomosis in a duodeno-ileostomy bipartition
Semaglutide Drug

Semaglutide (up to 2.4mg subcutaneous (SQ) injection weekly or dose tolerated according to side effects); a glucagon-like peptide-1 receptor agonist (GLP-1RA)

Main thing measured	Functional improvement of T2D: HbA1c
Sponsor	GT Metabolic Solutions, Inc.
Conditions studied	Obesity (Disorder), Obesity & Overweight, Type 2 Diabetes (T2DM)
GLP-1 drugs	semaglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT07317115 ↗