STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss

NCT06571383 · Active, not recruiting

Last updated 2026-05-28

This study tests whether the medication semaglutide helps teenagers with obesity maintain a healthy weight.

Status Active, not recruiting Ongoing, but no longer enrolling new participants.

Phase Phase 4 Monitors a drug already on the market.

Type Interventional (clinical trial)

Design open-label (no blinding) treatment study

Participants 500 people Planned (estimated).

Who can join Ages 12–15 · all sexes

Timeline Started 2024-09 · est. completion 2031-11

Where 93 sites · Belgium, Canada, Denmark, France, Germany, Greece, Italy, Mexico, Poland, Saudi Arabia, Sweden, United Kingdom, United States

What this study is testing ClinicalTrials.gov NCT06571383 ↗

Description as written by the study sponsor.

The study is testing how well semaglutide can help adolescents with excess body weight to lose weight and to maintain weight loss. All participants in the study will receive semaglutide as a weekly injection. The study medicine is injected with a thin needle in the stomach, thighs or upper arms. All participants will get semaglutide treatment for a minimum of 3 years.

Treatments tested

Semaglutide Drug

Participants will receive semaglutide s.c(under the skin) once weekly.

Main thing measured	Maintenance of Body Mass Index (BMI) below obesity threshold
Sponsor	Novo Nordisk A/S
Conditions studied	Obesity
GLP-1 drugs	semaglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT06571383 ↗