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Does Personality Predict Patient Adherence, Health Behaviors, and Weight Loss Outcomes During the Latino Crossover Semaglutide Study (LCSS)? (Story-LCSS Project)

NCT05622045 · Active, not recruiting

Last updated 2026-05-28

This clinical trial is studying whether personality traits can help predict how well Latino patients will follow their treatment plan, adopt healthy habits, and lose weight while taking semaglutide.

Status Active, not recruiting Ongoing, but no longer enrolling new participants.
Type Observational
Participants 59 people
Who can join Ages 18–74 · all sexes
Timeline Started 2023-02 · est. completion 2026-05
Where 1 site · United States

What this study is testing ClinicalTrials.gov NCT05622045 ↗

Description as written by the study sponsor.

The goal of this observational study is to learn about the personality attributes and values of people living with obesity that are part of the Latino community, and how these personality attributes and values can help to predict success during a weight loss program. The main questions it aims to answer are: * What are the personality attributes and values of people living with obesity that sign up to the LCSS-Latino Crossover Semaglutide Study trial? * Can behavioral artificial intelligence (a computer formula) predict which patients will complete the LCSS-Latino Crossover Semaglutide Study trial? * How do behavioral artificial Intelligence predictions (a computer formula) compare to clinician predictions of patient success? * Can behavioral artificial intelligence (a computer formula) predict patient weight loss, calorie consumption and physical activity levels during the LCSS-Latino Crossover Semaglutide Study trial? Participants will be recorded in English and Spanish while responding to a question regarding participation in a weight loss study.

Treatments tested

Main thing measuredPredicted patient weight change success
SponsorLoma Linda University
Conditions studiedObesity, Body Weight Changes
GLP-1 drugs semaglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT05622045 ↗