A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes

NCT05433584 · Active, not recruiting

Last updated 2026-05-28

This clinical trial is testing the medication tirzepatide against standard diabetes care in adults with type 2 diabetes to see how it affects their blood sugar levels over time.

Status Active, not recruiting Ongoing, but no longer enrolling new participants.

Phase Phase 4 Monitors a drug already on the market.

Type Interventional (clinical trial)

Design Randomized, open-label (no blinding) treatment study

Participants 780 people Planned (estimated).

Who can join Ages 18+ · all sexes

Timeline Started 2022-08 · est. completion 2027-11

Where 90 sites · Argentina, Canada, Germany, Israel, Italy, Mexico, Puerto Rico, Romania, Slovakia, United Kingdom, United States

What this study is testing ClinicalTrials.gov NCT05433584 ↗

Description as written by the study sponsor.

This study aims to investigate the efficacy and safety of tirzepatide in participants with type 2 diabetes (T2D) compared to other existing treatment options when treatment is initiated early.

Treatments tested

Tirzepatide also known as LY3298176 Drug

Administered SC
Antihyperglycemic medication Drug

As prescribed

Main thing measured	Change from Baseline in Hemoglobin A1c (HbA1c)
Sponsor	Eli Lilly and Company
Conditions studied	Type 2 Diabetes
GLP-1 drugs	tirzepatide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT05433584 ↗