A Multiple Dose Study of LY3502970 in Healthy Participants

NCT05051566 · Completed

Last updated 2026-05-28

This clinical trial tests the effects of multiple doses of the drug LY3502970 in healthy adults to measure how the body processes it.

Status Completed The study has finished.

Phase Phase 1 Checks safety and dosing in a small group.

Type Interventional (clinical trial)

Design Randomized, single-blind basic-science study

Participants 26 people

Who can join Ages 18–65 · all sexes Healthy volunteers accepted.

Timeline Started 2021-09 · est. completion 2022-04

Where 1 site · United Kingdom

What this study is testing ClinicalTrials.gov NCT05051566 ↗

Description as written by the study sponsor.

The main purpose of this study is to assess how fast LY3502970 gets into the blood stream and how long it takes the body to remove it when administered in multiple oral doses as new formulation compared to that of reference LY3502970 formulation. Information about safety and tolerability will be collected. The study is open to healthy participants. The study is conducted in two parts and it will last up to about 6 months, inclusive of screening period.

Treatments tested

LY3502970 Drug

Administered orally.
Esomeprazole Drug

Administered orally.

Main thing measured	Pharmacokinetics (PK): Maximum Observed Concentration (Cmax) of LY3502970
Sponsor	Eli Lilly and Company
Conditions studied	Healthy
GLP-1 drugs	—

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT05051566 ↗