Effect of GLP-1 Receptor Agonists on Trabecular Bone Score

NCT04964388 · Terminated

Last updated 2026-05-28

This clinical trial is testing how GLP-1 receptor agonists affect bone health in postmenopausal women who have both osteoporosis and type 2 diabetes.

Status Terminated Stopped early and will not restart.

Phase Phase 2 Tests whether it works and watches safety in a moderate group.

Type Interventional (clinical trial)

Design Non-randomized, open-label (no blinding) treatment study

Participants 5 people

Who can join Ages 55+ · female only

Timeline Started 2021-11 · est. completion 2023-07

Where 1 site · United States

What this study is testing ClinicalTrials.gov NCT04964388 ↗

Description as written by the study sponsor.

This study will help determine the effect of Glucagon Like Peptide-1 (GLP-1)receptor agonists on bone strength in postmenopausal women with type 2 diabetes mellitus (T2DM)

Treatments tested

GLP-1 receptor agonist Drug

Diabetes medication

Main thing measured	Trabecular Bone Score
Sponsor	University of Mississippi Medical Center
Conditions studied	Osteoporosis, Postmenopausal, Diabetes Mellitus, Type 2
GLP-1 drugs	—

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT04964388 ↗