A Research Study to See How Much Semaglutide and SNAC is in the Milk of Healthy, Breastfeeding Women Taking Semaglutide Tablets

NCT04817644 · Completed

Last updated 2026-05-28

This study is testing how much semaglutide, a medication for type 2 diabetes, appears in the breast milk of healthy women who are breastfeeding and taking semaglutide tablets.

Status Completed The study has finished.

Phase Phase 1 Checks safety and dosing in a small group.

Type Interventional (clinical trial)

Design open-label (no blinding) treatment study

Participants 14 people

Who can join Ages 18+ · female only Healthy volunteers accepted.

Timeline Started 2021-09 · est. completion 2023-07

Where 2 sites · United States

What this study is testing ClinicalTrials.gov NCT04817644 ↗

Description as written by the study sponsor.

Participants in the study, will receive the study drug once daily for 10 days in tablet form for oral (by mouth) intake. On day 1 to 5 the tablet will contain 3 mg semaglutide, and on day 6-10 the tablet will contain 7 mg semaglutide.

Treatments tested

Oral semaglutide Drug

Oral semaglutide once daily for a total of 10 days

Main thing measured	Area under the semaglutide milk concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,sema,D10,milk)
Sponsor	Novo Nordisk A/S
Conditions studied	Diabetes Mellitus, Type 2
GLP-1 drugs	semaglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT04817644 ↗