Liraglutide as Add on Therapy on Metformin in Women With Polycystic Ovary Syndrome

NCT02483299 · Completed

Last updated 2026-05-28

This clinical trial is testing whether adding the medication liraglutide to metformin helps reduce body weight in women who have polycystic ovary syndrome (PCOS) and obesity.

Status Completed The study has finished.

Phase Phase 4 Monitors a drug already on the market.

Type Interventional (clinical trial)

Design Randomized, open-label (no blinding) treatment study

Participants 40 people

Who can join Ages 18–55 · female only

Timeline Started 2014-01 · est. completion 2015-04

Where 1 site · Slovenia

What this study is testing ClinicalTrials.gov NCT02483299 ↗

Description as written by the study sponsor.

The purpose of this study was to determine whether combined treatment with liraglutide and metformin is more effective than metformin as monotherapy in the treatment of obese women with polycystic ovary syndrome (PCOS). We anticipated greater changes in body weight in patients on combined treatment than in those on monotherapy.

Treatments tested

Metformin also known as Glucophage tablets Drug
Glucophage tablets and Victoza also known as Glucophage tablets and Victoza 6 mg/ml solution for injection in pre-filled pen Drug

Main thing measured	Change in body weight
Sponsor	University Medical Centre Ljubljana
Conditions studied	PCOS, Obesity
GLP-1 drugs	liraglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT02483299 ↗