Efficacy and Mechanism of Exenatide on Improving Heart Function in Type 2 Diabetes With Heart Failure Patients

NCT02344641 · Unknown status

Last updated 2026-05-28

This clinical trial tests whether the medication exenatide improves heart function in adults with both type 2 diabetes and heart failure over a 4-week period.

Status Unknown status The sponsor has not confirmed the status recently.

Phase Not applicable Not a phased drug trial (e.g. a device or behavioral study).

Type Interventional (clinical trial)

Design Randomized, open-label (no blinding) treatment study

Participants 234 people Planned (estimated).

Who can join Ages 18–65 · all sexes

Timeline Started 2015-01 · est. completion 2016-12

What this study is testing ClinicalTrials.gov NCT02344641 ↗

Description as written by the study sponsor.

The study evaluates the efficacy of heart function improvements in type 2 diabetes and heart failure patients with exenatide, and also investigates the mechanisms of exenatide improving heart function.

Treatments tested

Exenatide Drug

Main thing measured	The change in plasma NT-proBNP level after using exenatide for 4 weeks
Sponsor	Chinese Academy of Medical Sciences, Fuwai Hospital
Conditions studied	Type 2 Diabetes Mellitus, Heart Failure
GLP-1 drugs	exenatide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT02344641 ↗