Safety Evaluation of Adverse Reactions in Diabetes

NCT02092597 · Completed

Last updated 2026-05-28

This clinical trial is testing the safety of a treatment by monitoring heart rate in adults with type 2 diabetes.

Status Completed The study has finished.

Phase Phase 4 Monitors a drug already on the market.

Type Interventional (clinical trial)

Design Randomized, open-label (no blinding) treatment study

Participants 42 people

Who can join Ages 35–70 · all sexes

Timeline Started 2013-10 · est. completion 2016-09

Where 1 site · Czechia

What this study is testing ClinicalTrials.gov NCT02092597 ↗

Description as written by the study sponsor.

The purpose of this study is to assess the effects of incretin-based antidiabetic therapies (DPP-4 inhibitors and GLP-1 agonists) on cardiovascular, gastrointestinal and renal system and to detail the mechanisms underlying their action in these systems.

Treatments tested

Exenatide Drug
Linagliptin Drug
Gliclazide Drug

Main thing measured	Heart rate
Sponsor	Charles University, Czech Republic
Conditions studied	Type 2 Diabetes Mellitus
GLP-1 drugs	—

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT02092597 ↗