Blood Pressure Outcomes With Liraglutide Therapy

NCT01755572 · Completed

Last updated 2026-05-28

This clinical trial tested whether the medication liraglutide affects blood pressure in adults with type 2 diabetes and high systolic blood pressure by measuring changes in a specific hormone (ANP) after one day.

Status Completed The study has finished.

Phase Phase 4 Monitors a drug already on the market.

Type Interventional (clinical trial)

Design Randomized, triple-blind basic-science study

Participants 22 people

Who can join Ages 30–70 · all sexes

Timeline Started 2013-01 · est. completion 2014-03

Where 1 site · Canada

What this study is testing ClinicalTrials.gov NCT01755572 ↗

Description as written by the study sponsor.

Purpose: The purpose of this study is to further study the mechanism by which liraglutide, a relatively new anti-hyperglycemic medication, might lower blood pressure in patients with Type 2 diabetes and high blood pressure.

Treatments tested

Liraglutide also known as Victoza Drug

Single cross-over study, 1 arm starting with liraglutide for 3 weeks crossed-over to placebo for 3 weeks, and 1 arm starting with placebo with cross-over to liraglutide for 3 weeks.
Placebo Drug

Single cross-over study, 1 arm starting with liraglutide for 3 weeks crossed-over to placebo for 3 weeks, and 1 arm starting with placebo with cross-over to liraglutide for 3 weeks.

Main thing measured	Change in plasma ANP level at 1 Day
Sponsor	Mount Sinai Hospital, Canada
Conditions studied	Type 2 Diabetes, Systolic Hypertension
GLP-1 drugs	liraglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT01755572 ↗