DIabetes REsearCh on Patient sTratification (DIRECT): GLP-1R Agonists

NCT01575301 · Completed

Last updated 2026-05-28

This clinical trial is testing the effects of GLP-1 receptor agonists on people with diabetes to see how their blood sugar levels change over 6 months.

Status Completed The study has finished.

Phase Not applicable Not a phased drug trial (e.g. a device or behavioral study).

Type Interventional (clinical trial)

Design open-label (no blinding) basic-science study

Participants 411 people

Who can join Ages 18–80 · all sexes

Timeline Started 2011-03 · est. completion 2015-12

Where 4 sites · United Kingdom

What this study is testing ClinicalTrials.gov NCT01575301 ↗

Description as written by the study sponsor.

The purpose of this study is to collect a cohort of patients treated with GLP-1R Agonists and to assess phenotypic, genetic and genomic biomarkers of glycaemic response to these agents.

Treatments tested

Exenatide, Liraglutide also known as Byetta, Victoza Drug

Dosage, frequency and duration not specified by protocol

Main thing measured	Change in HbA1c between baseline and 6 months
Sponsor	University of Dundee
Conditions studied	Diabetes
GLP-1 drugs	—

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT01575301 ↗