Liraglutide Effects on Memory in Healthy Subjects

NCT01550653 · Completed

Last updated 2026-05-28

This clinical trial tests whether the medication liraglutide affects memory in healthy adults.

Status Completed The study has finished.

Phase Phase 1 Checks safety and dosing in a small group.

Type Interventional (clinical trial)

Design Randomized, triple-blind basic-science study

Participants 40 people

Who can join Ages 18–35 · male only Healthy volunteers accepted.

Timeline Started 2012-05 · est. completion 2013-12

Where 1 site · Germany

What this study is testing ClinicalTrials.gov NCT01550653 ↗

Description as written by the study sponsor.

This study examines the hypothesis, that subcutaneous administration of liraglutide, an analogue of the incretin glucagon-like peptide 1, over 5 weeks improves memory functions in healthy humans.

Treatments tested

liraglutide also known as Victoza Drug

Subcutaneous self-administration of liraglutide(Victoza)by pen. The starting dose is 0.6 mg once daily(day 0 to 7), followed by 1.2 mg once daily (day 8 to 35).
Placebo Drug

Main thing measured	Change from Baseline in the immediate and delayed recall of a declarative memory task (word list recall) at time points indicated in "time frame" section.
Sponsor	University of Luebeck
Conditions studied	Healthy
GLP-1 drugs	liraglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT01550653 ↗