Comparison of Liraglutide Injected at Three Different Injection Sites in Healthy Volunteers

NCT01513525 · Completed

Last updated 2026-05-28

This clinical trial tested how liraglutide, a diabetes medication, is absorbed when injected into the abdomen, thigh, or upper arm in healthy volunteers.

Status Completed The study has finished.

Phase Phase 1 Checks safety and dosing in a small group.

Type Interventional (clinical trial)

Design Randomized, open-label (no blinding) treatment study

Participants 21 people

Who can join Ages 18–50 · all sexes

Timeline Started 2007-02 · est. completion 2007-05

Where 1 site · Germany

What this study is testing ClinicalTrials.gov NCT01513525 ↗

Description as written by the study sponsor.

This trial is conducted in Europe. the aim of this trial is to compare the pharmacokinetic profile of liraglutide between administrations in the thigh versus the abdomen and between administrations in the upper arm versus the abdomen.

Treatments tested

liraglutide Drug

Single dose of 0.60 mg administered subcutaneously in three different injection sites on three separate dosing visits

Main thing measured	Area under the Curve (AUC) of liraglutide for each injection site
Sponsor	Novo Nordisk A/S
Conditions studied	Diabetes, Healthy
GLP-1 drugs	liraglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT01513525 ↗