Efficacy of Laparoscopic Sleeve Gastrectomy and Intensive Medical Management in Obese Type 2 Diabetes

NCT01429506 · Completed

Last updated 2026-05-28

This clinical trial tests whether laparoscopic sleeve gastrectomy surgery combined with intensive medical treatment helps people with obesity and type 2 diabetes lose weight.

Status Completed The study has finished.

Phase Not applicable Not a phased drug trial (e.g. a device or behavioral study).

Type Interventional (clinical trial)

Design Randomized, open-label (no blinding) treatment study

Participants 30 people

Who can join Ages 20–70 · all sexes

Timeline Started 2011-01 · est. completion 2012-08

Where 1 site · India

What this study is testing ClinicalTrials.gov NCT01429506 ↗

Description as written by the study sponsor.

In this the investigators will be comparing the effects of Laparoscopic sleeve gastrectomy with intensive medical management on weight and metabolic parameters.

Treatments tested

Sleeve gastrectomy also known as Bariatric surgery, Laparoscopic sleeve gastrectomy Procedure

Sleeve gastrectomy
Intensive medical management Drug

Exenatide 10 mcg BD, Metformin 2-3 gm/day, 800 Kcal diet

Main thing measured	weight loss
Sponsor	Post Graduate Institute of Medical Education and Research, Chandigarh
Conditions studied	Diabetes Mellitus, Obesity
GLP-1 drugs	—

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT01429506 ↗