Comparison Between GLP 1 Analogues and DPP 4 Inhibitors in Type 1 Diabetes Mellitus

NCT01235819 · Completed

Last updated 2026-05-28

This clinical trial compares two types of medications, GLP-1 analogues and DPP-4 inhibitors, in adults with Type 1 Diabetes to see how they affect insulin needs.

Status Completed The study has finished.

Phase Phase 4 Monitors a drug already on the market.

Type Interventional (clinical trial)

Design Randomized, open-label (no blinding) treatment study

Participants 20 people

Who can join Ages 12–30 · all sexes

Timeline Started 2010-11 · est. completion 2011-09

Where 1 site · India

What this study is testing ClinicalTrials.gov NCT01235819 ↗

Description as written by the study sponsor.

To study the effects of GLP 1 analogues and DPP 4 inhibitors on newly detected type 1 diabetes patients.

Treatments tested

Insulin also known as Premixed Insulin Drug

Exenatide Sitagliptin
Sitagliptin also known as DPP 4 inhibitors Drug

Sitagliptin 100 mg per day oral
Exenatide also known as GLP 1 analogues Drug

Exenatide 10 micrograms daily twice

Main thing measured	change in insulin requirement
Sponsor	Command Hospital, India
Conditions studied	Type 1 Diabetes
GLP-1 drugs	—

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT01235819 ↗