A Study to Determine the Efficacy and Safety of Albiglutide as Compared With Liraglutide.

NCT01128894 · Completed

Last updated 2026-05-28

This clinical trial compares the effects of the medications albiglutide and liraglutide on blood sugar control in adults with type 2 diabetes.

Status Completed The study has finished.

Phase Phase 3 Confirms effectiveness in a large group before approval.

Type Interventional (clinical trial)

Design Randomized, open-label (no blinding) treatment study

Participants 841 people

Who can join Ages 18+ · all sexes

Timeline Started 2010-05 · est. completion 2011-09

Where 173 sites · Australia, Israel, Peru, Philippines, South Korea, Spain, United Kingdom, United States

What this study is testing ClinicalTrials.gov NCT01128894 ↗

Description as written by the study sponsor.

This open-label study examines the efficacy and safety of albiglutide as compared with liraglutide in subjects with type 2 diabetes.

albiglutide Biologic

albiglutide weekly subcutaneous injection
liraglutide Drug

liraglutide daily subcutaneous injection, starting at 0.6mg, then up-titrating to 1.2mg then 1.8mg in accordance with prescribing information.

Main thing measured	Mean Change From Baseline in Glycosylated Hemoglobin (HbA1c) at Week 32
Sponsor	GlaxoSmithKline
Conditions studied	Diabetes Mellitus, Type 2
GLP-1 drugs	liraglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT01128894 ↗