Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

NCT00331851 · Completed

Last updated 2026-05-28

This clinical trial tested the effect of the medication liraglutide on blood sugar control in adults with type 2 diabetes.

Status Completed The study has finished.

Phase Phase 3 Confirms effectiveness in a large group before approval.

Type Interventional (clinical trial)

Design Randomized, double-blind treatment study

Participants 584 people

Who can join Ages 18–80 · all sexes

Timeline Started 2006-05 · est. completion 2007-04

Where 116 sites · Argentina, Austria, Brazil, Denmark, Finland, France, India, Italy, Netherlands, Norway, Philippines, Poland, Russia, Serbia and Montenegro, Slovakia, South Africa, Spain, United Kingdom

What this study is testing ClinicalTrials.gov NCT00331851 ↗

Description as written by the study sponsor.

This trial is conducted in Africa, Asia, Europe and South America. This trial is designed to show the effect of treatment with liraglutide added to existing glimepiride and metformin combination therapy and to compare it with the effects of insulin glargine added to combination therapy of glimepiride and metformin.

Treatments tested

liraglutide Drug
insulin glargine Drug
metformin Drug
glimepiride Drug

Main thing measured	HbA1c
Sponsor	Novo Nordisk A/S
Conditions studied	Diabetes, Diabetes Mellitus, Type 2
GLP-1 drugs	liraglutide

Full protocol, eligibility, and contacts on ClinicalTrials.gov NCT00331851 ↗