Injection site reaction

11,541 FAERS reports across 10 drugs

Last updated 2026-05-28 15:46 UTC

A red, sore, or swollen area on the skin where a shot was given.

Plain-language definition of the term.

FDA labels for Mounjaro, Saxenda, Soliqua, Trulicity, Victoza, Wegovy, Xultophy, and Zepbound list injection site reactions as an adverse reaction reported in clinical trials.

AI summary of the sources below.

FAERS report counts (as of 2026Q1) reflect voluntary adverse-event reports and cannot establish causation or true frequency; higher counts often track prescription volume. openFDA FAERS ↗

Reports by drug

Drug	FAERS reports	Quarter
Mounjaro	3,758	2026Q1
Zepbound	2,992	2026Q1
Trulicity	1,617	2026Q1
Bydureon	1,516	2026Q1
Victoza	787	2026Q1
Byetta	535	2026Q1
Saxenda	211	2026Q1
Wegovy	85	2026Q1
Soliqua	39	2026Q1
Adlyxin	1	2026Q1

Mentioned in FDA labels

Mounjaro Adverse reactions
Saxenda Adverse reactions
Soliqua Adverse reactions
Trulicity Adverse reactions
Victoza Adverse reactions
Wegovy Adverse reactions
Xultophy Adverse reactions
Zepbound Adverse reactions

Research mentioning injection site reaction (1)

Tirzepatide-Induced Injection Site Reaction. Cureus · 2023 · 10 citations