GLPwatch
Papers (9189)
Page 33 of 154, ranked by citation count.
- Exendin-4 alleviates high glucose-induced rat mesangial cell dysfunction through the AMPK pathway.
- An overview of new GLP-1 receptor agonists for type 2 diabetes.
- Pharmacokinetic and pharmacodynamic modeling of exendin-4 in type 2 diabetic Goto-Kakizaki rats.
- Lesions of area postrema and subfornical organ alter exendin-4-induced brain activation without preventing the hypophagic effect of the GLP-1 receptor agonist.
- Dulaglutide Modulates the Development of Tissue-Infiltrating Th1/Th17 Cells and the Pathogenicity of Encephalitogenic Th1 Cells in the Central Nervous System.
- Cost-utility analysis of liraglutide compared with sulphonylurea or sitagliptin, all as add-on to metformin monotherapy in Type 2 diabetes mellitus.
- Synthesis and evaluation of human serum albumin-modified exendin-4 conjugate via heterobifunctional polyethylene glycol linkage with protracted hypoglycemic efficacy.
- Drug induced acute pancreatitis: does it exist?
- Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R).
- Drugs developed for treatment of diabetes show protective effects in Alzheimer's and Parkinson's diseases.
- Novel fusion of GLP-1 with a domain antibody to serum albumin prolongs protection against myocardial ischemia/reperfusion injury in the rat.
- Tirzepatide did not impact metabolic adaptation in people with obesity, but increased fat oxidation.
- Anti-diabetic effects of GLP1 analogs are mediated by thermogenic interleukin-6 signaling in adipocytes.
- As Semaglutide's Popularity Soars, Rare but Serious Adverse Effects Are Emerging.
- Relationship between residual gastric content and peri-operative semaglutide use assessed by gastric ultrasound: a prospective observational study.
- Efficacy and Safety of Tirzepatide in Adults With Type 1 Diabetes: A Proof of Concept Observational Study.
- Clinical use of liraglutide in type 2 diabetes and its effects on cardiovascular risk factors.
- Effects of liraglutide and sibutramine on food intake, palatability, body weight and glucose tolerance in the gubra DIO-rats.
- Exenatide-loaded microsphere/thermosensitive hydrogel long-acting delivery system with high drug bioactivity.
- Mechanism of the beneficial and protective effects of exenatide in diabetic rats.
- Management of hyperglycemia with the administration of intravenous exenatide to patients in the cardiac intensive care unit.
- Effective nose-to-brain delivery of exendin-4 via coadministration with cell-penetrating peptides for improving progressive cognitive dysfunction.
- Effects of GLP-1 Analogues and Agonists on the Gut Microbiota: A Systematic Review.
- The protective effects of lixisenatide against inflammatory response in human rheumatoid arthritis fibroblast-like synoviocytes.
- Editor's Choice- Pathophysiology and therapy of myocardial ischaemia/reperfusion syndrome.
- Alterations in energy balance following exenatide administration.
- Exenatide corrects postprandial hyperglycaemia in young people with cystic fibrosis and impaired glucose tolerance: A randomized crossover trial.
- Efficacy and Tolerability of Exenatide Once Weekly Over 6 Years in Patients with Type 2 Diabetes: An Uncontrolled Open-Label Extension of the DURATION-1 Study.
- Effects of glucagon-like peptide-1 on advanced glycation endproduct-induced aortic endothelial dysfunction in streptozotocin-induced diabetic rats: possible roles of Rho kinase- and AMP kinase-mediated nuclear factor κB signaling pathways.
- Risk of Malignant Neoplasia with Glucagon-Like Peptide-1 Receptor Agonist Treatment in Patients with Type 2 Diabetes: A Meta-Analysis.
- GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats.
- A polyphenol-metal nanoparticle platform for tunable release of liraglutide to improve blood glycemic control and reduce cardiovascular complications in a mouse model of type II diabetes.
- Effect of liraglutide on blood pressure: a meta-analysis of liraglutide randomized controlled trials.
- Incretin agents in type 2 diabetes.
- Improvement of psoriasis during exenatide treatment in a patient with diabetes.
- Effects of Tirzepatide on the Clinical Trajectory of Patients With Heart Failure, Preserved Ejection Fraction, and Obesity.
- Antiobesity efficacy of GLP-1 receptor agonist liraglutide is associated with peripheral tissue-specific modulation of lipid metabolic regulators.
- Presynaptic GLP-1 receptors enhance the depolarization-evoked release of glutamate and GABA in the mouse cortex and hippocampus.
- Stromal cell-derived factor-1/Exendin-4 cotherapy facilitates the proliferation, migration and osteogenic differentiation of human periodontal ligament stem cells in vitro and promotes periodontal bone regeneration in vivo.
- Clinical pharmacology of incretin therapies for type 2 diabetes mellitus: implications for treatment.
- Superior weight loss with once-weekly semaglutide versus other glucagon-like peptide-1 receptor agonists is independent of gastrointestinal adverse events.
- GLP-1 signaling preserves cardiac function in endotoxemic Fischer 344 and DPP4-deficient rats.
- Pancreatitis Risk Associated with GLP-1 Receptor Agonists, Considered as a Single Class, in a Comorbidity-Free Subgroup of Type 2 Diabetes Patients in the United States: A Propensity Score-Matched Analysis.
- Liraglutide in clinical practice: dosing, safety and efficacy.
- The role of endothelial nitric oxide in the anti-restenotic effects of liraglutide in a mouse model of restenosis.
- Effectiveness of liraglutide 3 mg for the treatment of obesity in a real-world setting without intensive lifestyle intervention.
- Similar efficacy and safety of once-weekly dulaglutide in patients with type 2 diabetes aged ≥65 and <65 years.
- Practical Use of Pharmacotherapy for Obesity.
- Liraglutide improves carotid intima-media thickness in patients with type 2 diabetes and non-alcoholic fatty liver disease: an 8-month prospective pilot study.
- Exendin-4 Reverses Biochemical and Functional Alterations in the Blood-Brain and Blood-CSF Barriers in Diabetic Rats.
- Lixisenatide attenuates the detrimental effects of amyloid β protein on spatial working memory and hippocampal neurons in rats.
- Incretin-based therapies in the management of type 2 diabetes: rationale and reality in a managed care setting.
- One-year sustained glycemic control and weight reduction in type 2 diabetes after addition of liraglutide to metformin followed by insulin detemir according to HbA1c target.
- Ophthalmic Complications Associated With the Antidiabetic Drugs Semaglutide and Tirzepatide.
- Liraglutide improves vascular dysfunction by regulating a cAMP-independent PKA-AMPK pathway in perivascular adipose tissue in obese mice.
- Human embryonic stem cell differentiation into insulin secreting β-cells for diabetes.
- Effects of glucagon-like peptide-1 receptor agonists on secretions of insulin and glucagon and gastric emptying in Japanese individuals with type 2 diabetes: A prospective, observational study.
- Liraglutide alleviates H<sub>2</sub>O<sub>2</sub>-induced retinal ganglion cells injury by inhibiting autophagy through mitochondrial pathways.
- Effects of liraglutide on no-reflow in patients with acute ST-segment elevation myocardial infarction.
- Continued efforts to translate diabetes cardiovascular outcome trials into clinical practice.