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The unseen risk of Ozempic: NAION and vision damage.

Ann Med Surg (Lond) · 2025

Last updated 2026-08-28
JournalAnn Med Surg (Lond), 2025
Citations0
Molecules semaglutide

Abstract

Ozempic (semaglutide) was first authorized to treat type 2 diabetes, but because of its appetite-suppressing properties, it has become popular off-label for weight loss. According to clinical investigations, GLP-1 significantly decreases blood sugar and helps people lose weight. Approximately 15 million persons in the United States are currently taking GLP-1 drugs. Off-label use is becoming more common, which raises worries about potential health hazards and significant side effects such as non-arteritic anterior ischemic optic neuropathy (NAION). According to a study, 6.7% of people who were overweight and 8.9% of those with diabetes who took semaglutide had NAION. The FDA issued a warning regarding counterfeit and compounded products while approving semaglutide for weight loss under the Wegovy brand. Unsupervised usage and problems with diabetes accessibility raise ethical questions.

Verbatim abstract via PubMed 41377330 ↗

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