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In adults with overweight or obesity and CVD, but without diabetes, semaglutide reduced MACE at a mean 40 mo.

Ann Intern Med · 2024

Last updated 2026-05-28

In a study of 17,604 adults with overweight or obesity and cardiovascular disease but without diabetes, those taking semaglutide had a 20% lower risk of major cardiovascular events over an average of 40 months compared to those taking a placebo.

AI summary of the abstract below.

JournalAnn Intern Med, 2024
Citations2
Relative citation ratio0.20
NIH percentile13
Molecules semaglutide
Conditions studied Obesity, Cardiovascular Risk Reduction

Abstract

Lincoff AM, Brown-Frandsen K, Colhoun HM, et al; SELECT Trial Investigators. N Engl J Med. 2023;389:2221-2232. 37952131.

Verbatim abstract via PubMed 38437690 ↗

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