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Tirzepatide-Induced Biphasic Anaphylactic Reaction: A Case Report.

Cureus · 2023

Last updated 2026-07-01
JournalCureus, 2023
Citations7
Relative citation ratio0.99
NIH percentile50
Molecules tirzepatide

Abstract

Anaphylaxis is a rapid and severe reaction to a trigger that is characterized by skin, mucosal, and cardiorespiratory changes. A minority of patients exhibit a biphasic anaphylactic reaction (BAR). Tirzepatide is a dual incretin receptor analog approved for the treatment of type 2 diabetes mellitus (T2DM). Allergic reactions to tirzepatide were reported during clinical trials, but none were severe enough to be characterized as an anaphylactic reaction. We describe a case of a BAR to tirzepatide.

Verbatim abstract via PubMed 38186543 ↗

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