GLPwatch

Bile acid diarrhoea.

Ugeskr Laeger · 2023

Last updated 2026-05-28

Bile acid diarrhoea is a condition where bile acids irritate the colon, causing diarrhoea and affecting about 1-2% of adults. Current treatment uses bile acid sequestrants, but a study found that the GLP-1 drug liraglutide may be more effective at reducing symptoms.

AI summary of the abstract below.

JournalUgeskr Laeger, 2023
Citations0
Relative citation ratio0.00
NIH percentile0
Molecules

Abstract

Bile acid diarrhoea is a socially debilitating disease caused by irritation of the colonic mucosa due to a spillover of bile acids from the small intestine into the colon. Studies estimate a prevalence of 1-2% of the adult population, but many patients never seek help or are misdiagnosed. Bile acid diarrhoea is treated with bile acid sequestrants, however, new research shows superior effect on reported symptoms with the glucagon-like peptide 1 receptor agonist liraglutide.

Verbatim abstract via PubMed 37264870 ↗