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[Does liraglutide have a place in psychiatry ?]

Rev Med Suisse · 2022

Last updated 2026-05-28

A study explored whether liraglutide, a GLP-1 drug, could help people with serious mental illnesses who also have obesity, type 2 diabetes, or metabolic syndrome. Liraglutide is already used to treat type 2 diabetes and obesity, and the study found no concerning psychiatric side effects that would prevent its use in this group.

AI summary of the abstract below.

JournalRev Med Suisse, 2022
Citations0
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Molecules liraglutide
Conditions studied Depression, Anxiety

Abstract

The relative risk of developing MetS is higher in patients with severe mental illness (SMI) than in the general population. Similarly, the risk of developing obesity or type 2 diabetes (T2DM) is also higher in patients with SMI. GLP-1 receptor agonists, such as liraglutide, have been shown to be effective in the treatment of T2DM and, more recently, in obesity or overweight associated with at least one metabolic disease. Their psychiatric adverse effect profiles seem to be reassuring, thus not represent a limitation for prescribing in psy chiatry. We aimed to explore the therapeutic usefulness of liraglutide in patients with psychiatric disorders associated with somatic comorbidities such as obesity, T2DM or MetS.

Verbatim abstract via PubMed 35343120 ↗

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