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In type 2 diabetes with increased CV risk, tirzepatide reduced HbA<sub>1c</sub> vs. glargine at 52 wk.

Ann Intern Med · 2022

Last updated 2026-05-28

In a study of 1,877 adults with type 2 diabetes and increased cardiovascular risk, tirzepatide reduced blood sugar control (measured by HbA1c) more than glargine over 52 weeks. The average starting HbA1c was 8.26%, and the average reduction was 2.19% with tirzepatide compared to 1.44% with glargine.

AI summary of the abstract below.

JournalAnn Intern Med, 2022
Citations2
Relative citation ratio0.11
NIH percentile8
Molecules tirzepatide
Conditions studied Type 2 Diabetes, Cardiovascular Risk Reduction

Abstract

Del Prato S, Kahn SE, Pavo I, et al. Lancet. 2021;398:1811-24. 34672967.

Verbatim abstract via PubMed 35226523 ↗

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