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In adults with overweight or obesity, continued weekly semaglutide after a 20-wk run-in improved weight loss.

Ann Intern Med · 2021

Last updated 2026-05-28

In a study of 1,961 adults with overweight or obesity, participants who took weekly semaglutide for 48 weeks after a 20-week initial treatment period lost an average of 17.4% of their body weight, compared to 2.6% in those who switched to a placebo after the initial period.

AI summary of the abstract below.

JournalAnn Intern Med, 2021
Citations3
Relative citation ratio0.13
NIH percentile9
Molecules semaglutide
Conditions studied Obesity

Abstract

Rubino D, Abrahamsson N, Davies M, et al. JAMA. 2021;325:1414-25. 33755728.

Verbatim abstract via PubMed 34339232 ↗

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