GLPwatch

Imaging of Insulinoma by Targeting Glucagonlike Peptide-1 Receptor.

PET Clin · 2021

Last updated 2026-05-28

GLP-1 receptor imaging, which uses a radioactive version of the drug exendin-4, has been shown to effectively detect insulinomas—tumors that cause low blood sugar—in patients with hyperinsulinemic hypoglycemia. This method is highly accurate for locating these tumors before surgery, according to clinical research.

AI summary of the abstract below.

JournalPET Clin, 2021
Citations7
Relative citation ratio0.77
NIH percentile41
Molecules
Conditions studied Type 2 Diabetes

Abstract

"Glucagonlike peptide-1 (GLP-1) receptor imaging, using radiolabeled exendin-4, was recently established for detecting insulinoma in patients with hyperinsulinemic hypoglycemia. It has proven to be a sensitive and specific method for preoperative localization of insulinoma. This review introduces the development, clinical research, and perspective of GLP-1 receptor imaging mainly in insulinoma.

Verbatim abstract via PubMed 33589387 ↗