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Variables associated with insulin production in persons with type 2 diabetes treated with multiple daily insulin injections.
Prim Care Diabetes · 2021
Last updated 2026-05-28In people with type 2 diabetes using multiple daily insulin injections, lower natural insulin production was linked to having diabetes for a longer time, a shorter abdominal sagittal diameter, and greater swings in blood sugar levels. These findings were based on measurements of C-peptide, proinsulin, and the proinsulin-to-C-peptide ratio at the start of the study.
AI summary of the abstract below.
| Journal | Prim Care Diabetes, 2021 |
|---|---|
| Citations | 0 |
| Relative citation ratio | 0.00 |
| NIH percentile | 0 |
| Molecules | — |
| Conditions studied | Type 2 Diabetes |
Abstract
From the MDI-liraglutide study, we evaluated variables associated with endogenous insulin production in persons with multiple daily insulin injections-treated type 2 diabetes by relating C-peptide, proinsulin and proinsulin/C-peptide ratio at baseline to baseline variables. Lower insulin production was related to longer diabetes duration, shorter abdominal sagittal diameter and more glycaemic variability.
Verbatim abstract via PubMed 33303380 ↗