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[Effect of liraglutide in treatment of non-alcoholic fatty liver disease: mechanism of action and research advances].

Zhonghua Gan Zang Bing Za Zhi · 2017

Last updated 2026-05-28

Liraglutide is a drug used to treat type 2 diabetes that may also help people with non-alcoholic fatty liver disease, a condition linked to obesity, high blood fats, and diabetes. Research suggests it has some effect on the liver disease, but scientists do not yet fully understand how it works.

AI summary of the abstract below.

JournalZhonghua Gan Zang Bing Za Zhi, 2017
Citations0
Relative citation ratio0.00
NIH percentile0
Molecules liraglutide
Conditions studied Mash

Abstract

Non-alcoholic fatty liver disease is a common chronic liver disease closely associated with obesity, hyperlipidemia, and diabetes. It can gradually progress to liver cirrhosis or even hepatocellular carcinoma; however, there are still no specific therapeutic agents for this disease. Liraglutide is a human glucagon-like peptide-1 analogue and has a marked effect in the treatment of type 2 diabetes. At present, many studies indicate that liraglutide also has a certain therapeutic effect on non-alcoholic fatty liver disease during the treatment of type 2 diabetes, but its mechanism of action remains unknown. This article reviews the known mechanisms of action of liraglutide in the treatment of non-alcoholic fatty liver disease.

Verbatim abstract via PubMed 28763870 ↗

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