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A case report: Liraglutide as a novel treatment option in late dumping syndrome.

Medicine (Baltimore) · 2017

Last updated 2026-05-28

A patient with late dumping syndrome—low blood sugar after meals following stomach surgery—was treated with liraglutide injections at doses of 0.6 mg and 1.2 mg per day. The treatment reduced insulin spikes and improved symptoms of low blood sugar, suggesting liraglutide may be a new option for this condition.

AI summary of the abstract below.

JournalMedicine (Baltimore), 2017
Citations18
Relative citation ratio0.97
NIH percentile49
Molecules liraglutide

Abstract

RATIONALE: Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging. PATIENT CONCERNS: New-onset postsurgical late dumping syndrome after Toupet fundoplication. DIAGNOSES: Sigstad Score, OGTT, CGM. INTERVENTIONS: Daily subcutaneous injection of liraglutide (0.6 mg and 1.2 mg). OUTCOMES: Reduction in fasting and postprandial peak insulin level with improvement in symptomatic hypoglycemic events. LESSONS: Liraglutide may be a novel treatment option for postprandial hyperinsulinemic hypoglycemia after gastric surgery.

Verbatim abstract via PubMed 28328816 ↗

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