The treatment of hidradenitis suppurativa with the glucagon-like peptide-1 agonist liraglutide.
Br J Dermatol · 2017
Last updated 2026-05-28A single patient with hidradenitis suppurativa (HS), a skin condition linked to inflammation and obesity, was treated with the GLP-1 drug liraglutide. After treatment, the patient lost weight and showed improved control of their HS symptoms. This is the first reported case of liraglutide being used for HS.
AI summary of the abstract below.
| Journal | Br J Dermatol, 2017 |
|---|---|
| Citations | 44 |
| Relative citation ratio | 2.42 |
| NIH percentile | 79 |
| Molecules | liraglutide |
Abstract
Hidradenitis suppurativa (HS) is a cutaneous disease associated with systemic inflammation, obesity and metabolic syndrome. Effective treatment options are limited. The antidiabetic agents, incretins, have been used successfully to treat psoriasis - a disease also associated with metabolic syndrome. We report the use of liraglutide, a glucagon-like peptide-1 agonist, in a patient with HS, leading to subsequent weight loss and improvement in disease control. To our knowledge, this is the first report of liraglutide used in the treatment of HS.
Verbatim abstract via PubMed 27943236 ↗
Related research
- Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes.
- A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.
- Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study.
- Liraglutide and Renal Outcomes in Type 2 Diabetes.
- Efficacy of Liraglutide for Weight Loss Among Patients With Type 2 Diabetes: The SCALE Diabetes Randomized Clinical Trial.
- The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss.
- Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial.
- The Discovery and Development of Liraglutide and Semaglutide.