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Answers to Clinical Questions in the Primary Care Management of People with Obesity: Pharmacologic Management.

J Fam Pract · 2016

Last updated 2026-05-28

Five medications—liraglutide, lorcaserin, naltrexone/bupropion extended-release, phentermine/topiramate extended-release, and orlistat—are now approved for long-term weight loss in adults with overweight (BMI of 27 or higher with at least one weight-related health issue) or obesity (BMI of 30 or higher). These drugs offer new options for managing weight in primary care settings.

AI summary of the abstract below.

JournalJ Fam Pract, 2016
Citations2
Relative citation ratio0.07
NIH percentile6
Molecules
Conditions studied Obesity

Abstract

The recent approval of liraglutide, lorcaserin, naltrexone/bupropion extended-release, and phentermine/topiramate extended-release, brings the number of medications for long-term weight loss to 5 (including orlistat). Indicated for the treatment of patients with overweight (body mass index [BMI] ≥27 kg/m2 with ≥1 weight-related comorbidity) or obesity (BMI ≥30 kg/m2), these medications provide new opportunities to address this burgeoning health problem.

Verbatim abstract via PubMed 27565106 ↗