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Clinical effects of liraglutide are possibly influenced by hypertriglyceridemia and remaining pancreatic β-cell function in subjects with type 2 diabetes mellitus.
J Diabetes Complications · 2016
Last updated 2026-05-28In people with type 2 diabetes, higher blood fats (triglycerides) and higher initial blood sugar levels were linked to better short-term control of blood sugar when taking liraglutide. Lower remaining pancreatic beta-cell function at the start was linked to longer-lasting effects of the drug.
AI summary of the abstract below.
| Journal | J Diabetes Complications, 2016 |
|---|---|
| Citations | 6 |
| Relative citation ratio | 0.22 |
| NIH percentile | 14 |
| Molecules | liraglutide |
| Conditions studied | Type 2 Diabetes |
Abstract
We searched for factors influencing the clinical effects of GLP-1 analogue liraglutide in subjects with type 2 diabetes. Multivariate analyses showed that hypertriglyceridemia and baseline HbA1c levels were independent predictors for the efficacy of liraglutide and that CPR index was an independent predictor for the durability of liraglutide.
Verbatim abstract via PubMed 27220544 ↗
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