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68Ga-NOTA-Exendin-4 PET/CT in Localization of an Occult Insulinoma and Appearance of Coexisting Esophageal Carcinoma.

Clin Nucl Med · 2016

Last updated 2026-05-28

A 61-year-old woman with severe low blood sugar caused by an insulin-producing tumor in her pancreas underwent a PET/CT scan using a special radioactive tracer. The scan correctly identified the tumor in her pancreas, which was later confirmed by surgery. The same scan did not detect a separate esophageal cancer found in her body, which was identified by a different type of PET/CT scan.

AI summary of the abstract below.

JournalClin Nucl Med, 2016
Citations12
Relative citation ratio0.68
NIH percentile38
Molecules
Conditions studied Type 2 Diabetes

Abstract

A 61-year-old woman with biochemically proven endogenous hyperinsulinemic hypoglycemia and negative conventional imaging underwent 68Ga-NOTA-exendin-4 PET/CT for localization of insulinoma. Focal intense radioactivity in the tail of the pancreas was observed that was subsequently confirmed as insulinoma pathologically after surgical resection. In addition, esophageal carcinoma with lymph node and hepatic metastases was found by FDG PET/CT in the same patient. Neither the primary carcinoma nor the metastases showed increased radioactivity on 68Ga-NOTA-exendin-4 PET/CT.

Verbatim abstract via PubMed 26647001 ↗