GLPwatch

Soliqua for Depression

lixisenatide · Investigational / off-label

Last updated 2026-05-28 15:46 UTC

Soliqua (lixisenatide) is not FDA-approved for depression, and any use for this condition is off-label or investigational. Research in mice suggests lixisenatide may influence neurogenesis and reduce depression-like symptoms, but these findings have not been confirmed in humans.

AI summary of the sources below.

DrugSoliqua (lixisenatide)
ConditionDepression
Approval statusInvestigational / off-label
Research papers2

Soliqua is not FDA-approved for depression; the research below reflects investigational or off-label study only.

Research on lixisenatide for depression (2)

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