GLPwatch

Adlyxin for MASH (metabolic dysfunction-associated steatohepatitis)

lixisenatide · Investigational / off-label

Last updated 2026-05-28 15:46 UTC

Adlyxin (lixisenatide) is not FDA-approved for MASH. A systematic review with individual patient data meta-analysis of randomized controlled trials in type 2 diabetes patients found that lixisenatide reduced elevated liver transaminases, which may suggest potential benefits for liver health.

AI summary of the sources below.

DrugAdlyxin (lixisenatide)
ConditionMASH (metabolic dysfunction-associated steatohepatitis)
Approval statusInvestigational / off-label
Research papers1

Adlyxin is not FDA-approved for mash (metabolic dysfunction-associated steatohepatitis); the research below reflects investigational or off-label study only.

Research on lixisenatide for mash (metabolic dysfunction-associated steatohepatitis) (1)

Search PubMed ↗