Hair loss
Investigational / off-label
Last updated 2026-05-28 15:46 UTCMultiple studies and reviews report hair loss as a potential adverse effect associated with GLP-1 receptor agonist use, including semaglutide and tirzepatide, with some analyses suggesting a disproportionality signal in adverse event reporting systems.
AI summary of the sources below.
Approved GLP-1 drugs (0)
No GLP-1 drug is FDA-approved for hair loss in our data. Any research below reflects investigational or off-label study.
Research (16)
- Implications of Ozempic and Other Semaglutide Medications for Facial Plastic Surgeons.
- GLP-1 receptor agonist impairs keratinocytes inflammatory signals by activating AMPK.
- Alopecia associated with the use of semaglutide and tirzepatide: A disproportionality analysis using the FDA adverse event reporting system (FAERS) from 2022 to 2023.
- Risk of Suicide, Hair Loss, and Aspiration with GLP1-Receptor Agonists and Other Diabetic Agents: A Real-World Pharmacovigilance Study.
- Glucagon-like peptide-1 receptor agonist medications and hair loss: A retrospective cohort study.
- Letter to the Editor: Comment on Implications of Ozempic and Other Semaglutide Medications for Facial Plastic Surgeons.
- Weighing in on glucagon-like peptide-1 receptor agonists in dermatology.
- Hair Loss Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Use: A Systematic Review.
- Glucagon-like peptide-1 receptor agonists and hair loss: An emerging clinical concern.
- Predictors and Characteristics of Hair Loss Among Users of GLP-1 Receptor Agonists: A Cross-Sectional Analysis.
- GLP-1 therapies and hair loss: A systematic review of current evidence and implications for counseling.
- Alopecia as an Emerging Adverse Effect Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists for Weight Loss: A Scoping Review.
- Effects of GLP-1 Receptor Agonists on Hair Loss and Regrowth: A Systematic Review.
- Risk of new-onset hair loss with semaglutide and tirzepatide: A TriNetX cohort study.
- Impact of GLP-1 and GLP-1/GIP agonists on healthcare resource utilization in individuals with scarring alopecias: A retrospective cohort analysis using TriNetX.
- Prevalence and Predictors of Hair Shedding among GLP-1 Receptor Agonist Users: A Cross-Sectional Study from Saudi Arabia.
Common questions
- Which GLP-1 drugs are FDA-approved for Hair loss?
- No GLP-1 drug is currently FDA-approved for hair loss; any use would be off-label or investigational.
- Is there research on GLP-1 drugs for Hair loss?
- GLPwatch tracks 16 research papers on GLP-1 drugs and hair loss. This research is investigational and does not imply FDA approval.