GLPwatch

Dulaglutide vs Exenatide

Molecule comparison

Last updated 2026-05-28 15:46 UTC

Dulaglutide (brand name Trulicity) and Exenatide (brand names Byetta and Bydureon) are both GLP-1 receptor agonists, a type of medication that helps control blood sugar. Dulaglutide is FDA-approved to treat type 2 diabetes and reduce cardiovascular risk, while Exenatide is approved only for type 2 diabetes. Dulaglutide is given as a once-weekly injection, whereas Exenatide comes in two forms: a twice-daily injection (Byetta) and a once-weekly injection (Bydureon).

AI summary of the sources below.

Dulaglutide Exenatide
MechanismGLP-1 receptor agonistGLP-1 receptor agonist
StatusApprovedApproved
Branded productstrulicitybyetta, bydureon

Compare full details on the Dulaglutide and Exenatide pages.